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. 2018 Apr 3;8(22):12484–12493. doi: 10.1039/c8ra00870a

Fig. 6. In vivo implantation of MBG and PTHrP-1-MBG scaffolds into the rat posterolateral spinal fusion site; micro-CT images show oblique view of the rat spinal column at the implant site 12 weeks post-implantation. Bone formation and complete bridging of two transverse processes was observed through oblique view of CT images in the 0.5 mg PTHrP-1-MBG (A) and 0.1 mg PTHrP-1-MBG (B) scaffold groups, which indicates successful fusion. A clear gap between two transverse processes was observed in MBG group (C), resulting in failure of posterolateral spinal fusion (n = 6 per group); SP, spinous process; TP, transverse process. (D) BMD and (E) BV/TV varied in every group (*P < 0.05).

Fig. 6