Fig. 4. Effect of BBAP-1 upon cellular, morphological and surface architecture of mammary gland tissue: carmine staining of tissue revealed the presence of AB1 (1), AB2 (2), and lobules (3) in respective groups (A, B, C and D). The numbers of ABs and lobules were high in the toxic group (B) and reduced in the treatment groups (C and D). H&E staining of four respective groups (E, F, G and H) revealed ducts (4), MECs (5), CECs (6), LCT (7), DCT (8), lymphocytes (9) and adipocytes (10). In toxic control group (F), the cellular histology was distorted. SEM analysis of control (I) group revealed collagenous covering. Treatment with MNU shows loss of collagenous cushions (11), formation of ducts (12), development of tumor micro-vessels (13) and large blood vessels (14). MNU treatment induces cellular proliferation and treatment with BBAP-1 shows protection against deleterious effects of MNU.