Fig. 1. Schematic illustration and characterization of nanohybrids. (A) Schematic illustration of the construction of FA/PS/miR-34a/PS@NDs through self-assembly approach. (B) Surface zeta potential of nanohybrids which was expressed as means ± S.D (n = 3). (C) The size distribution of nanohybrids, which was expressed as means ± S.D (n = 3). (D) TEM imaging. (a) PS/NDs, (b) miR-34a/PS@NDs, (c) PS/miR-34a/PS@NDs, (d) FA/PS/miR-34a/PS@NDs. (e) Magnified TEM image of the marked part in (d). (f) The corresponding FFT pattern of FA/PS/miR-34a/PS@NDs. The scale bars represent 5 nm.