Fig. 6. In vivo antitumor activity. (A) Tumor volumes were measured at shown time-points and demonstrated as average of duplicate measurements with standard error bars (n = 5) for each group, **p < 0.01. (B) The tumors volumes were calculated at time of sacrifice and presented as mean ± SD, **p < 0.01. (C) miR-34a level was quantitatively measured by RT-PCR and shown as mean ± SD, **p < 0.01. (D) Expression of Fra-1 was quantitatively analyzed by RT-PCR and demonstrated as mean ± SD, **p < 0.01. (E) Expression of Fra-1 was detected by western blot. (F) Representative data of H&E staining of tumor tissues. Scale bar: 50 μm.
