Experimental data and observed response values with different combinations of extraction time (A, min), extraction temperature (B, °C) and solvent-to-solid ratio (C, mL g⁻¹) used in BBD.

Run	Factor			Extraction yield/(mg g−1)
	A	B	C	Aloe-emodin	Rhein	Emodin	Chrysophanol	Physcion	Total anthraquinones
1	1.5	80	25	2.27	5.55	2.19	6.07	9.18	25.26
2	2.0	70	25	2.17	4.14	2.07	5.42	7.37	21.17
3	1.5	80	25	2.27	5.48	2.19	6.04	9.18	25.16
4	1.0	70	25	1.99	5.40	1.70	4.83	6.81	19.93
5	1.5	70	20	2.12	4.16	1.83	4.79	7.77	20.67
6	1.0	80	20	2.49	3.68	1.85	5.19	7.61	20.42
7	2.0	80	20	2.02	4.44	1.84	4.85	8.26	21.41
8	2.0	90	25	2.16	3.92	1.98	5.14	8.27	21.68
9	1.0	90	25	2.13	5.13	2.07	5.28	7.31	21.84
10	1.0	80	30	2.14	4.11	1.98	5.14	8.27	21.64
11	2.0	80	30	2.01	5.64	2.13	5.04	6.99	21.81
12	1.5	70	30	2.05	4.63	1.80	4.94	7.12	20.54
13	1.5	80	25	2.31	5.36	2.16	6.17	9.27	25.27
14	1.5	80	25	2.70	5.78	2.22	5.87	8.81	25.38
15	1.5	80	25	2.45	5.27	2.20	6.19	8.97	25.08
16	1.5	80	30	2.10	4.30	1.88	5.34	8.78	22.40
17	1.5	80	25	2.16	4.11	1.88	5.14	7.72	21.01