Percentage inhibition values of MCF-7/1B1 cell proliferation with treatment of 10 μM CYP1B1 inhibitors and 20 μM docetaxel.
| Compound | clog Pa | % inhibition |
|---|---|---|
| Medium | — | 7.6 |
| 5h | 3.5 | 33.3 |
| 5g | 3.7 | 22.5 |
| 5c | 3.7 | 21.6 |
| 5e | 4.4 | 26.1 |
| 5f | 3.5 | 20.1 |
| 4a | 5.6 | 20.5 |
| ANF | 4.7 | 26.3 |
clog P values were predicted by ChemBioDraw Ultra 12.0.