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. 2018 Apr 20;8(27):15009–15020. doi: 10.1039/c8ra00465j

Percentage inhibition values of MCF-7/1B1 cell proliferation with treatment of 10 μM CYP1B1 inhibitors and 20 μM docetaxel.

Compound clog Pa % inhibition
Medium 7.6
5h 3.5 33.3
5g 3.7 22.5
5c 3.7 21.6
5e 4.4 26.1
5f 3.5 20.1
4a 5.6 20.5
ANF 4.7 26.3
a

clog P values were predicted by ChemBioDraw Ultra 12.0.