Table 3.
Genotype frequencies of CTLA4 + 49A/G and IL4 -590C/T polymorphism in HCV induced HCC patients and Control groups
| Gene | Genetype | Patient (n = 213) | Control (n = 216 | Odds ratio | 95% CI –odds ratio | Relative risk | 95% CI—relative risk | P value |
|---|---|---|---|---|---|---|---|---|
| n, (%) | n, (%) | |||||||
| CTLA4 | AG | 134 (62.9%) | 55 (25.5%) | 4.96 | 3.29 -7.52 | 2.154 | 1.76—2.64 | < 0.0001 |
| GG | 79 (37.1%) | 161 (74.5%) | 0.20 | 0.13—0.30 | 0.4643 | 0.37—0.56 | < 0.0001 | |
| IL4 | CC | 138 (64.8%) | 60 (27.8%) | 4.78 | 3.19 -7.17 | 2.14 | 1.75—2.65 | < 0.0001 |
| CT | 46 (21.6%) | 136 (62.9%) | 0.16 | 0.11—0.25 | 0.37 | 0.28—0.48 | < 0.0001 | |
| TT | 29 (13.6%) | 20 (9.3%) | 1.54 | 0.84—2.84 | 1.22 | 0.91—1.53 | 0.17 |