Table 4.

Gender based genotype frequencies comparison of CTLA4 + 49A/G and IL4 -590C/T polymorphism in HCV induced HCC patients and Control groups

Gene	Gender based genotypes	HCV induced HCC %	Control %	Oddsratio	95% CI-odds ratio	Relativerisk	95% CI- relative risk	P value
		Present	Present
CTLA4	Male AG	28.50%	18.65%	4.46	2.43—8.26	2.11	1.66–2.87	< 0.0001
	Male GG	18.65%	28.50%	0.22	0.12—0.41	0.47	0.34 -0.63	< 0.0001
	Female AG	33.62%	18.30%	5.32	3.06—9.35	2.16	1.66—2.85	< 0.0001
	Female GG	35.25%	64.75%	0.18	0.11—0.33	0.46	0.35 -0.60	< 0.0001
IL4	Male CC	32.64%	16.06%	5.15	2.80 -9.56	2.37	1.70—3.37	< 0.0001
	Male CT	9.84%	31.61%	0.17	0.09—0.34	0.37	0.24—0.55	< 0.0001
	Male TT	4.66%	5.18%	1.01	0.41—2.70	1.01	0.56 -1.51	> 0.99
	Female CC	31.91%	12.34%	4.62	2.68—8.04	2.01	1.56—2.62	< 0.0001
	Female CT	11.49%	31.91%	0.14	0.083 -0.25	0.37	0.26—0.51	< 0.0001
	Female TT	8.51%	3.83%	2.26	0.99—5.42	1.39	1.00—1.77	0.07