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. 2018 May 3;8(29):16383–16391. doi: 10.1039/c8ra02240b

Cytotoxicity of compounds 1–16 (IC50 in μM)a on A549 and K562 cells.

Compounds A549 K562 Compounds A549 K562
1a 10
2a 11 36.8 18.4
3a 12 35.0 17.5
4 33.6 16.8 13 17.6
5 13.6 6.7 14 16.7
6 13.1 14.6 15 34.2 7.5
7 35.3 16 11.2
8 Adriamycin 2.9 2.0
9
a

Presents a pair of enantiomers; “–” presents IC50 values > 50 μM.