DNA-binding constant (Kb), thermal denaturation Tm (°C), DNA-apparent binding constant (Kapp), BSA-quenching constant (Kq), BSA-binding constant (Kbin) and number of binding sites (n) of the bis(thiosemicarbazone)copper(i) complexes (1–6).
| Complexes | K b × 105 (M−1) | T m (°C) | K app × 105 (M−1) | K q × 105 (M−1) | K bin × 105 (M−1) | ‘n’ value |
|---|---|---|---|---|---|---|
| 1 | 4.91 ± 0.11 | 68.7 ± 0.82 | 2.3 ± 0.16 | 2.87 ± 1.12 | 2.33 ± 0.18 | 1.31 |
| 2 | 6.01 ± 0.48 | 69.9 ± 0.11 | 3.0 ± 0.52 | 3.48 ± 1.13 | 3.28 ± 1.32 | 1.75 |
| 3 | 5.93 ± 0.12 | 69.7 ± 0.19 | 2.9 ± 0.57 | 3.36 ± 0.22 | 3.17 ± 0.91 | 1.64 |
| 4 | 5.42 ± 0.65 | 69.1 ± 0.31 | 2.6 ± 1.02 | 3.11 ± 0.48 | 2.79 ± 0.75 | 1.48 |
| 5 | 4.44 ± 0.27 | 68.1 ± 0.16 | 1.4 ± 1.18 | 2.49 ± 0.74 | 2.13 ± 0.88 | 1.21 |
| 6 | 2.81 ± 0.79 | 66.5 ± 0.19 | 1.1 ± 1.04 | 2.06 ± 0.97 | 1.54 ± 0.52 | 1.09 |
| Cisplatin | 0.32 ± 0.15 | — | — | — | — | — |