Table 5.

Univariate and Multivariate Cox Regression Analysis for OS in HCC Patients with Tumor

	Univariate Cox regression				Multivariate Cox regression
Variables	P-value	HR	95% CI		P-value	HR	95% CI
Risk score(high/low)	0	2.59	1.38	4.87	0	2.32	1.43	3.77
Age (>60/≤60)	0.46	0.81	0.45	1.44
BMI	0.79
<25		Reference
≥25		1	0.53	1.88
Not reported	0.54	1.43	0.45	4.55
Race	0.77
Non-Asian		Reference
Asian		1.1	0.48	2.55
AFP	0.49	2.11	0.26	17.31
≤20ng/mL		Reference
˃20ng/ml		1.77	0.84	3.73
Not reported		2.42	1.04	5.63
Gender (Male/Female)	0.14	1.63	0.85	3.14
Hepatitis B or C	1
No		Reference
Yes		0.99	0.46	2.12
Not reported		0	0	4.02E+251
Alcohol	0.31
No		Reference
Yes		0.7	0.35	1.4
Cirrhosis	0.52
No		Reference
Yes		1.6	0.61	4.22
Not reported		1.39	0.65	2.95
Histologic grade	0.5
G1-2		Reference
G3-4		1.05	0.55	1.99
Not reported		0.31	0.04	2.28
New tumor event	0.25
No		Reference
Yes		0.95	0.32	2.85
Not reported		6.5	0.53	79.9
Pathologic stage	0.12
Stage I+II		Reference
Stage III+IV		2	1.02	3.94
Not reported		1.87	0.72	4.88
Family cancer history	0.12
No		Reference
Yes		1.44	0.76	2.73
Not reported		0.45	0.13	1.55
Residual tumor	0.14
R0		Reference
Non-R0		0.3	0.09	1
Not reported		0.59	0.05	6.42
Vascular invasion	0
Negative		Reference				Reference
Positive		0.94	0.46	1.93	0.96	0.99	0.54	1.81
Not reported		3.23	1.51	6.91	0	2.57	1.53	4.32

BMI, Body mass index; AFP, Alpha fetoprotein; HR, Hazard ratio; CI, Confidence interval.