Table 4.

Genotype and Allele Frequency of Germline Mutations Found in Jordanian Patients with Colorectal Adenoma (N=50)

Variant identified	Nucleotide (wt/vt)**	Genotype frequency (wt/wt)* (wt/vt)** (vt/vt)***	Allele frequency (wt:vt)** N (%)
c.1941T>A	T:A	34 (68%) 16(32%) 0(0%)	T: 84 (84%) A:16 (16%)
g.73038C>T	C:T	25 (50%) 23(46%) 2(4%)
g.75508A>C	A:C	35 (70%) 11(22%) 4(8%)	A:81 (81%) C:19 (19%)
c.2201G>C	G>C	39 (78%) 11(22%) 0(0%)	G:89 (89%) C:11 (11%)

*, (Wild type/ wild type); **, (wild type/variant); ***, (variant type/ variant type)