Characteristics of drug-loaded fiber mats: wettability, loading contents and efficiency.
Sample | Fiber dia. (μm) | CA° | LC (wt%) | LE (wt%) | Morphology |
---|---|---|---|---|---|
PLA | 0.31 (±0.03) | 160° (±2.8) | NA | NA | Non-beaded, cylindrical fibers with grooves |
PLA–HCl | 0.32 (±0.05) | 139° (±14.6) | 3.5 (±0.2) | 74 (±3.2) | Large Dox-HCl aggregates from the surface |
PLA–base | 0.30 (±0.03) | 160° (±4.1) | 4.8 (±0.4) | 100 (±7.5) | Small Dox-base from the surface |
PLA–HCl(DMSO) | 0.39 (±0.05) | 148° (±2.4) | 5.1 (±0.1) | 107 (±2.0) | No observable Dox-HCl particles |