Three-component synthesis of 2-alkyl-4-amino-7-arylimidazo[1,2-a][1,3,5]triazines (5)^a.

^aThe reaction was performed using a Discover SP CEM microwave synthesizer with 1 mmol of 2-aminoimidazoles (1), 2.5 mmol of trialkyl orthoesters and 2.5 mmol of cyanamide at 160 °C for 35 min in 2 mL of ethyl acetate.