TABLE 2.
Number of strains exhibiting synergistic killing with GAT in combination with a nonquinolone agent
| Nonquinolone | Total no. of strains synergistic/no. of strains synergistic at sub-MIC
|
||||
|---|---|---|---|---|---|
| P. aeruginosa(n = 8) | P. stutzeri(n = 4) | B. cepacia(n = 6) | S. maltophilia(n = 8) | Acinetobacter spp. (n = 4) | |
| FEP | 3 | 2 | |||
| CAZ | 5 | 2 | 5/3a | 5/4a | 2/1a |
| CFP | 5/1a | 2 | |||
| IPM | 6/1a | 0 | 1/1b | 0 | |
| ATM | 6 | 3 | 4/1a, 3b | 4/3a, 1b | 2/2a |
| PIP | 7/2a | 3 | |||
| TIM | 5/1a | 2/1a | |||
| SXT | 0 | 2 | 1 | ||
| AMK | 3/1a | 3 | 1 | ||
| MIN | 1 | 0 | |||
| CHL | 0 | ||||
a
One drug in the two-drug combination was tested at sub-MIC level.
b
Both drugs in the two-drug combination were tested at sub-MIC levels.