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. 2001 Nov;45(11):3220–3222. doi: 10.1128/AAC.45.11.3220-3222.2001

TABLE 4.

Antimicrobial profile of S. maltophilia and Acinetobacter strains studied, including those killed synergistically with GAT-nonquinolone combinations

Species and strain MIC (μg/ml)ab
GAT CAZ ATM IMP TIM SXT AMK MIN
S. maltophilia(n = 8)
A27486 0.5 [64] 128 NT [8/2] 16/304 NT 0.25
A24069 0.5 8 64 4/2 64/1216 0.5
A24062 2 [4] [32] [1/2] 128/2432 0.5
A21816 1 [64] [64] [4/2] 32/608 [0.5]
A21384 4 [8] [64] 2/2 16/304 2
A25456 4 64 64 8/2 128/2432 0.5
A24258 2 64 64 [32/2] [2/38] 0.5
A24252 1 [32] [64] [2/2] [2/38] 0.5
Acinetobacter(n = 4)
A. lwoffii A9446 0.06 [16] [32] 0.13 [64/2] 2/38 0.13 0.13
A. lwoffiiA24961 1 16 16 0.5 2/2 0.25/4.75 16 0.25
A. baumanniiA21248 0.5 8 32 0.25 4/2 0.5/9.5 16 0.25
A. baumanniiA27439 0.13 [4] [32] 0.25 [4/2] [0.5/9.5] [1] 0.25
Susceptible breakpoint 2 8 8 4 16/2 2/38 16 4
a

Bracketed values represent those strains that were synergistically killed with the GAT-nonquinolone combination. NT, not tested. 

b

TIM values are the MIC of ticarcillin/the MIC of clavulanate; SXT values are the MIC of sulfamethoxazole/the MIC of trimethoprim.