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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Br J Pharmacol. 2022 Feb 10;179(11):2647–2658. doi: 10.1111/bph.15762

Figure 2. Systemic effects of the NOP antagonist LY2817412 on nicotine self-administration in NOP (+/+) and NOP (−/−) rats.

Figure 2.

(A) Number of responses (infusions and total number of active and inactive lever presses) following systemic LY2817412 administration (0.0, 1.0 and 3.0 mg/kg) in NOP (+/+) (n = 11) and (B) NOP (−/−) (n = 12) rats. ***p < 0.001 vs. 0.0 mg/kg vs 1.0 and 3.0 mg/kg. Values represent mean (± SEM).