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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Pharmacogenet Genomics. 2022 Feb 21;32(4):159–172. doi: 10.1097/FPC.0000000000000466

Table 5.

Linkage disequilibrium summary statistics and CYP2A6*1B and rs8192733 allele frequencies in EUR and AFR individuals

EUR (n=935); D’=0.94; R2=0.50
CYP2A6*1A CYP2A6*1B
rs8192733 Reference (C) 56% 1%
rs8192733 Variant (G) 14% 29%
AFR (n=506); D’=0.93; R2=0.75
CYP2A6*1A CYP2A6*1B
rs8192733 Reference (C) 80% 1%
rs8192733 Variant (G) 3% 16%

AFR: African-ancestry individuals; EUR: European-ancestry individuals