Table 1.
Demographic and clinical characteristics of study volunteers
| Healthy (n=38) | High PA PI-IBS (n=19) | Low PA PI-IBS (n=33) | ANOVA | |
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| Gender (Female, Male) | 24, 14 | 11, 8 | 19, 14 | |
| Age (Mean, SD) | 43, 14 | 43, 15 | 48, 18 | 0.36 |
| BMI (Mean, SD) | 28.16, 5.10 | 31.6, 8.45 | 29.8, 6.47 | 0.35 |
| Race (% Caucasian, total n) | 93.5, 31 | 100, 16 | 100, 29 | |
| HADS - Anxiety (Mean, SD, n) | 2.65, 2.85, 31 | 5.38, 3.91, 16 | 5.24, 2.66, 29 | <0.001 |
| HADS - Depression (Mean, SD, n) | 0.77, 1.2, 31 | 2.75, 2.98, 16 | 2.83, 2.56, 29 | <0.0001 |
| BM/Day (Mean, SD, n) | 1.36, 0.54, 37 | 2.80, 1.16, 19 | 1.77, 0.77, 31 | <0.0001 |
| Bristol Stool Form (Mean, SD, n) | 4.07, 0.67, 37 | 5.07, 0.55, 19 | 4.27, 1.11, 31 | <0.0001 |
| Ease of Passage (Mean, SD, n) | 4.00, 0.14, 37 | 4.63, 0.56, 19 | 4.19, 0.46, 31 | <0.0001 |
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| High PA PI-IBS | Low PA PI-IBS | p-value (t-test) | ||
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| IBS Subtype (C, D, M) | 0, 11, 8 | 3, 19, 11 | ||
| IBS SSS (Mean, SD) | 274.4, 118.6 | 203.3, 111.2 | 0.08 | |
| IBS QOL (Mean, SD) | 28.78, 18.22 | 21.58, 17.80 | 0.13 | |
*
Statistical analysis: Non-parametric One-way ANOVA with Dunn’s multiple comparison post-hoc and Student’s t-test. Standard deviation (SD), Body mass index (BMI, kg/m2), Hospital anxiety and depression score (HADS; 0–7 normal, 8–10 borderline abnormal, 11–21 abnormal), Bowel movement (BM), Bristol stool form (1:constipation-7:diarrhea), Ease of passage scale (1–7), IBS subtype (C: Constipation, D: Diarrhea, M: Mixed) Symptom severity score (SSS; 75–175 mild 175–300 moderate, >300 severe), Quality of life (QOL; 34–170).