Table 2.

Comparison of EoE characteristics between normal and abnormal contractile responses.

		‘Normal’ CRs	Abnormal CRs
n (%)		133 (67)	66 (33)
Age, years, mean (SD)		37 (12)	41 (12)*
Female, n (%)		52 (39)	12 (18)*
Symptom duration, years		7 (3–15)	10 (4–23)*
BEDQ score		5 (1–8)	3 (1–6)
[n (%) completed BEDQ]		[55 (41)]	[30 (45)]
Off treatment, n (%)		27 (20)	17 (26)
On PPI, n (%)		86 (65)	43 (65)
On topical steroid, n (%)		15 (11)	7 (11)
On elimination diet, n (%)		24 (18)	6 (9)
Previous dilation, n (%)		43 (32)	31 (47)*
Eosinophil count (eos/hpf)		25 (5–50)	34 (14–60)
Eosinophil count <15/hpf, n (%)		44 (33)	15 (23)
Endoscopic score (EREFS)
Edema score, n (%)	0	46 (35)	16 (24)
	1	87 (65)	50 (76)
Ring score, n (%)	0	18 (14)	5 (8)
	1	85 (64)	26 (39)*
	2	29 (22)	28 (42)*
	3	1 (1)	7 (11)*
Exudate score, n (%)	0	76 (57)	32 (48)
	1	42 (32)	26 (39)
	2	15 (11)	8 (12)
Furrow score, n (%)	0	33 (25)	15 (23)
	1	98 (74)	48 (73)
Stricture, n (%)	0	30 (23)	12 (18)
	1	102 (77)	54 (82)
Total EREFS score		4 (3–5)	5 (3–6)*
Total EREFS-Fibrotic score		2 (1–2)	3 (2–3)*
Total EREFS-Inflammatory score		2 (1–3)	2 (1–3)
FLIP metrics
Distensibility plateau (mm)		18 (15–19)	16 (12–19)*
Distensibility plateau <17mm, n (%)		43 (32)	37 (56)*
Distensibility plateau <13mm, n (%)		7 (5)	21 (32)*
Pressure, maximum FLIP fill volume (mmHg)		54 (46–67)	57 (49–70)
Maximum EGJ diameter (mm)		16 (14–18)	13 (12–14)*
Maximum EGJ diameter, n (%)
	<12mm	8 (6)	18 (27)*
	12–16mm	53 (40)	38 (58)*
	≥16mm	72 (54)	10 (15)*
EGJ-Distensiblity Index (DI) (mm2/mmHg)		3.3 (2.4–4.4)	1.7 (1.2–2.9)*
EGJ-DI, n (%)
	<2.0 mm2/mmHg	25 (19)	39 (59)*
	≥2.0 mm2/mmHg	108 (81)	27 (41)*

Values reported as median (IQR) unless otherwise noted.

^*P<0.05 on comparison with ‘Normal’ i.e. normal or borderline, contractile response (CR). Abnormal CRs included impaired/disordered (CR), absent CR, or spastic-reactive CR. Brief Esophageal Dysphagia Questionnaire (BEDQ) score completed on day of endoscopy with FLIP.