Table 3. Associations with abnormal contractile response.

The strength of association among each individual parameter with an abnormal contractile response (CR) was evaluated using univariable binary logistic regression; i.e. abnormal CR (impaired/disordered, absent, or spastic-reactive) was utilized as the dependent variable. hpf – high-powered field. Ref = reference category.

Univariable	B (SE)	OR (95% CI)	P
Age	0.03 (0.01)	1.0 (1.0–1.1)	0.015
Sex (male)	1.1 (0.4)	2.9 (1.4–5.9)	0.004
Symptom duration	0.05 (0.02)	1.1 (1.0–1.1)	0.002
On treatment	−0.3 (0.4)	0.7 (0.4–1.5)	0.383
Previous dilation (Yes)	0.6 (0.3)	1.9 (1.0–3.5)	0.038
Eosinophil count	0.01 (0.01)	1.0 (1.0–1.0)	0.208
Eosinophil count <15/hpf	−0.44 (0.34)	0.6 (0.3–1.3)	0.202
EREFS total score	0.2 (0.1)	1.3 (1.1–1.5)	0.005
EREFS Fibrotic score	0.6 (0.2)	1.9 (1.3–2.7)	<0.001
EREFS Inflammatory score	0.2 (0.1)	1.2 (0.9–1.5)	0.162
Stricture (Yes)	0.3 (0.4)	1.4 (0.7–2.9)	0.409
Distensibility plateau	−0.2 (0.5)	0.8 (0.7–0.9)	<0.001
Distensibility plateau <17mm	1.0 (0.3)	2.7 (1.5–4.9)	0.001
Distensibility plateau <13mm	2.1 (0.5)	8.4 (3.3–21.1)	<0.001
EGJ-distensibility index (DI)	−0.5 (0.1)	0.6 (0.5–0.7)	<0.001
EGJ-DI <2.0 mm 2 /mmHg	1.8 (0.3)	6.2 (3.2–12.0)	<0.001
Maximum EGJ diameter (FLIP)	−0.4 (0.1)	0.7 (0.6–0.8)	<0.001
Maximum EGJ diameter (FLIP)
<12mm	2.8 (0.5)	16.2 (5.6–47)	<0.001
12–16mm	1.6 (0.4)	5.2 (2.3–11.3)	<0.001
>=16mm	ref	ref
FLIP Pressure (greatest fill volume)	0.013 (0.01)	1.0 (1.0–1.10)	0.127