Table 2.
First day of hospital symptoms, vital signs, in deceased and surviving patients with COVID-19 infection
| Variable | All patients (n=51), n (%) | Death (n=24), n (%) | Survivors (n=27), n (%) | P |
|---|---|---|---|---|
| First day of hospital symptoms | ||||
| Fever — no./51 (%) | 32/51 (62.74) | 13/24 (54.16) | 19/27 (70.37) | 0.233 |
| Chills — no./51 (%) | 25/51 (49.01) | 12/24 (50) | 13/27 (48.14) | 0.896 |
| Dyspnea — no./51 (%) | 30/51 (58.82) | 14/24 (58.33) | 16/27 (59.25) | 0.947 |
| Cough — no./51 (%) | 34/51 (66.66) | 13/24 (54.16) | 21/27 (77.77) | 0.069 |
| Sore throat — no./51 (%) | 5/51 (9.80) | 1/24 (4.16) | 4/27 (14.81) | 0.196 |
| Anorexia — no./51 (%) | 9/51 (17.64) | 3/24 (12.50) | 6/27 (22.22) | 0.358 |
| Fatigue — no./51 (%) | 16/51 (31.37) | 9/24 (37.50) | 7/27 (25.92) | 0.373 |
| Nausea — no./51 (%) | 11/51 (21.56) | 3/24 (12.50) | 8/27 (29.62) | 0.142 |
| Vomiting — no./51 (%) | 10/51 (19.60) | 3/24 (12.50) | 7/27 (25.92) | 0.231 |
| Body ache/myalgia — no./51 (%) | 24/51 (47.05) | 6/24 (25) | 18/27 (66.66) | 0.001 |
| Abdominal pain — no./51 (%) | 3/51 (5.88) | 0/24 (0) | 3/27 (11.11) | 0.087 |
| Diarrhea — no./51 (%) | 8/51 (15.68) | 2/24 (8.33) | 6/27 (22.22) | 0.169 |
| Headache — no./51 (%) | 8/51 (15.68) | 0/24 (0) | 8/27 (29.62) | 0.005 |
| Dizziness — no./51 (%) | 1/51 (1.96) | 0/24 (0) | 1/27 (3.70) | 0.340 |
| Expectoration — no./51 (%) | 17/51 (33.33) | 5/24 (20.83) | 12/27 (44.44) | 0.069 |
| Chest pain — no./51 (%) | 0/51 (0) | 0/24 (0) | 0/27 (0) | - |
| Decrease level of consciousness (LOC) — no./51 (%) | 4/51 (7.84) | 2/24 (8.33) | 2/27 (7.40) | 0.90 |
| First day of hospital admission vital signs | ||||
| Median temperature (IQR) — °C | 38 (1.2) | 37.9 (1.2) | 38 (1.3) | 0.263 |
| Distribution of temperature≥37.8°C — no./total no. (%) | 28/45 (62.22) | 12/20 (60) | 16/25 (64) | 0.232 |
| Peripheral capillary oxygen saturation (SpO2) % | 85 (10) | 85 (12.75) | 87 (12) | 0.671 |
| SpO2<93% — no./total no. (%) | 43/51 (84.31) | 21/24 (87.50) | 22/27 (81.48) | 0.559 |
| Median respiratory rate (IQR) —/minutes | 25 (10) | 25 (10) | 26 (12) | 0.353 |
| Median heart rate (IQR) —/minutes | 99 (27) | 97 (29.25) | 100 (28) | 0.921 |
| Median systolic blood pressure (IQR) — mm Hg | 133 (25) | 139 (29.75) | 126 (29) | 0.144 |
| Median diastolic blood pressure (IQR) — mm Hg | 79.5 (12.75) | 75.5 (19.5) | 81 (10) | 0.182 |
| Median GCS score | 15 (0) | 15 (0) | 15 (0) | 0.380 |
| First day of hospital admission laboratory findings | ||||
| White-cell count | ||||
| Median (IQR) — per mm3 | 6500 (3500) | 6700 (3750) | 6500 (3500) | 0.261 |
| Distribution | ||||
| <4000 per mm3 — no./total no. (%) | 3/39 (7.69) | 1/18 (5.55) | 2/21 (9.52) | |
| 4000–10,000 per mm3 — no./total no. (%) | 31/39 (79.48) | 13/18 (72.22) | 18/21 (85.71) | |
| >10,000 per mm3 — no./total no. (%) | 5/39 (12.82) | 4/18 (22.22) | 1/21 (4.76) | |
| Lymphocyte count | ||||
| Median (IQR) — per mm3 | 830.20 (398.08) | 838.65 (494.22) | 814.55 (350.85) | |
| Distribution | ||||
| <1500 per mm3 — no./total no. (%) | 3/38 (7.89) | 2/18 (11.11) | 1/20 (5) | 0.487 |
| Neutrophil count | ||||
| Median (IQR) — per mm3 | 5103.6 (3598.55) | 5402.55 (4620.30) | 5103.6 (3450.02) | |
| Distribution | ||||
| <1800 per mm3 — no./total no. (%) | 3/38 (7.89) | 2/18 (11.11) | 1/20 (5) | 0.198 |
| 1800–7800 per mm3 — no./total no. (%) | 30/38 (78.94) | 12/18 (66.66) | 18/20 (90) | |
| >7800 per mm3 — no./total no. (%) | 5/38 (13.15) | 4/18 (22.22) | 1/20 (5) | |
| Platelet count | ||||
| Median (IQR) — per mm3 | 171,000 (66,000) | 174,500 (80,250) | 166,000 (52,500) | 0.749 |
| Distribution | ||||
| <150,000 per mm3 — no./total no. (%) | 14/39 (35.89) | 8/18 (44.44) | 6/21 (28.57) | - |
| Hb | ||||
| Median (IQR) — g/dL | 13.6 (2.9) | 13.2 (3.65) | 13.7 (2.6) | 0.679 |
| Hct | ||||
| Median (IQR) | 44.1 (9.33) | 43.1 (11.70) | 44.9 (8.6) | 0.414 |
| CRP | ||||
| Positive — no./total no. (%) | 29/34 (85.29) | 12/16 (75) | 17/18 (94.44) | 0.137 |
| ESR | ||||
| Median (IQR) — mm/h | 47 (44) | 66.5 (62.25) | 44 (25) | |
| >22 mm/h — no./total no. (%) | 30/35 (85.71) | 13/16 (81.25) | 17/19 (89.47) | 0.486 |
| PTT | ||||
| Median (IQR) — s | 33 (8.5) | 33 (8) | 33 (11) | |
| >39 s — no./total no. (%) | 6/34 (17.64) | 3/17 (17.64) | 3/17 (17.64) | 1.023 |
| PT | ||||
| Median (IQR) — s | 13 (0) | 13 (0.4) | 13 (0) | |
| >13 s — no./total no. (%) | 7/34 (20.58) | 4/17 (23.52) | 3/17 (17.64) | 0.669 |
| INR | ||||
| >1.2 — no./total no. (%) | 3/33 (9.09) | 2/16 (12.50) | 1/17 (5.88) | 0.513 |
| LDH | ||||
| Median (IQR) — U/l | 871 (544) | 936 (544) | 871 (167) | |
| >530 U/l — no./total no. (%) | 4/5 (80) | 1/2 (50) | 3/3 (100) | 0.174 |
| CPK | ||||
| >195 U/l — no./total no. (%) | 2/4 (50) | 1/2 (50) | 1/2 (50) | 0.997 |
| Trop positive — no./total no. (%) | 9/39 (23.07) | 6/18 (33.33) | 3/21 (14.28) | 0.417 |
| Cr | ||||
| Median (IQR) — µmol/l | 99.008 (48.62) | 96.356 (157.57) | 99.008 (30.498) | |
| ≥133 µmol/l — no./total no. (%) d4 | 9/39 (23.07) | 6/18 (33.33) | 3/21 (14.28) | 0.156 |
| AST | ||||
| Median (IQR) — U/l | 51 (40.75) | 46.5 (34.50) | 63 (61.5) | |
| >40 U/l — no./total no. (%) | 28/34 (82.35) | 13/16 (81.25) | 15/18 (83.33) | 0.869 |
| ALT | ||||
| Median (IQR) — U/l | 33.50 (36.25) | 22 (20.50) | 54 (36) | |
| >40 U/l — no./total no. (%) | 15/36 (41.66) | 4/17 (23.52) | 11/19 (57.89) | 0.037 |
| ALP | ||||
| Median (IQR) — U/l | 162 (67) | 155 (109.75) | 165 (66) | |
| >300 U/liter — no./total no. (%) | 4/35 (11.42) | 2/16 (12.50) | 2/19 (10.52) | 0.860 |
| Alb: | ||||
| Median (IQR) | 4 (1.06) | 3.985 (1.22) | 4.07 (0.70) | 0.451 |
| <5.2 — no./total no. (%) | 36/36 (100) | 16/16 (100) | 20/20 (100) | |
| T.Billi: | ||||
| Median (IQR) | 0.86 (0.55) | 0.87 (0.48) | 0.85 (0.65) | |
| >1.2— no./total no. (%) | 6/26 (23.07) | 3/14 (21.42) | 3/12 (25) | 0.884 |
| D.Billi: | ||||
| Median (IQR) | 0.25 (0.27) | 0.255 (0.32) | 0.24 (0.29) | |
| >0.3 — no./total no. (%) | 9/27 (33.33) | 4/14 (28.57) | 5/13 (38.46) | 0.583 |
IQR=Interquartile range; GCS=Glasgow Coma Scale; Hb=Hemoglobin; Hct: Hematocrit; CRP=C-reactive protein; ESR=Erythrocyte sedimentation rate; PTT=Partial thromboplastin time; PT=Prothrombin time; INR=International normalized ratio; LDH=Lactate dehydrogenase; CPK=Creatinine kinase; Cr=Creatinine; AST=Aminotransferase; ALT=Alanine aminotransferase; ALP=Alkaline phosphatase; Alb=Albumin; T.Billi=Total bilirubin; D.Billi=Direct bilirubin