TABLE 2.

Comparison of hexanol production performance obtained using C. carboxidivorans P7 with previous reports.

Type	Syngas supply				rpm	Temp (°C)	Working volume	Products (g/L) a						Reference
	CO	CO2	H2	kPa or mL/min				EtOH	BuOH	HeOH	AA	BA	HA
Bottle	70	10	20	307 kPa	0	37	30 ml (in 282 ml bottle)	2.05	1.09	0.94	0.73	0.32	0.36	Phillips et al. (2015)
Bottle	32	8	32	100 kPa	100	25	20 ml (in 125 ml bottle)	1.48	1.07	0.84	1.65	-	1.05	Ramió-Pujol et al. (2015)
Bottle	56	20	9	200 kPa	100	37/25	30 ml (in 125 ml bottle)	3.97	1.67	1.33	(0.2) b	(0.1) b	(0.1) b	Shen et al. (2017)
Bottle	40	20	20	101 kPa	150	37	50 ml (in 160 ml bottle)	3	0.27	-	0.05	0.11	-	(Cheng et al., 2019) c
Bottle	50	35	15	200 kPa	200	37	20 ml (in 120 ml bottle)	1.66	0.84	0.3	0.15	0.05	-	Han et al. (2020)
Bioreactor	50	35	15	400 ml/min	200	37	3 L (in 7 L bioreactor)	3.2	1	0.6	2	0.3	-	Han et al. (2020)
Bioreactor	100	-	-	10 ml/min	250	33	1.2 L (in 2 L bioreactor)	4.41	2.30	-	1.04	-	-	Fernández-Naveira et al. (2016)
Bioreactor	4.0 L/h CO (pCO = 800 mbar) and 1.0 L/h CO2 (pCO2 = 200 mbar)					37	1 L (in 2.4 L bioreactor)	1.17	0.56	0.16	0.96	0.21	0.08	Rückel et al. (2021)
Bottle	70	-	-	100 kPa	100	30	20 ml (in 157 ml bottle)	1.21	1.21	1.90	0.73	0.44	0.59	This study
Bottle (ethanol addition)	70	-	-	100 kPa	100	30	20 ml (in 157 ml bottle)	−0.45 d	1.60	2.34	0.82	0.38	0.41	This study

^aEtOH, ethanol; BuOH, butanol; HeOH, hexanol; AA, acetic acid; BA, butyric acid; HA, hexanoic acid.

^bApproximate values from graphs.

^c adh2 overexpression.

^dNegative value indicates a decrease in ethanol concentration. Ethanol concentration was decreased from 2.40 to 1.01 g/L during 144 h of fermentation and then increased to 1.95 g/L after 312 h of fermentation.