TABLE 1.
Basic characteristics of participants.
| Variables | Alprazolam Exposure Group (N = 96) | Alprazolam non-exposure Group (N = 629) | P-value | |||||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | |||||
| Age (years), Mean (SD) | 32.9 | (4.0) | 31.8 | (3.8) | 0.008 | |||
| Age | <35 | 68 | 70.8 | 506 | 80.4 | 0.031 | ||
| 35 | 28 | 29.2 | 123 | 19.6 | ||||
| Gravidity, mean (SD) | 2.2 | (1.3) | 2.2 | (1.2) | 0.928 | |||
| Parity | <1 | 48 | 50.0 | 276 | 43.9 | 0.261 | ||
| ≥1 | 48 | 50.0 | 353 | 56.1 | ||||
| BMI a | <18.5 (kg/m2) | 19 | 19.8 | 112 | 17.9 | 0.666 | ||
| ≥18.5 and <23 (kg/m2) | 60 | 62.5 | 378 | 60.5 | ||||
| ≥23 (kg/m2) | 17 | 17.7 | 135 | 21.6 | ||||
| Alcohol intake | 26 | 27.1 | 250 | 39.7 | 0.017 | |||
| Smoking | 11 | 11.5 | 56 | 8.9 | 0.421 | |||
| Radiation | 17 | 17.7 | 91 | 14.5 | 0.406 | |||
| Education Level | High school or less | 7 | 7.3 | 45 | 7.2 | 0.568 | ||
| College | 2 | 2.1 | 16 | 2.5 | ||||
| University | 41 | 42.7 | 223 | 35.5 | ||||
| No answer | 46 | 47.9 | 345 | 54.8 | ||||
| Occupation | White collar | 39 | 40.6 | 282 | 44.8 | 0.203 | ||
| Blue collar | 4 | 4.2 | 51 | 8.1 | ||||
| Housewife | 53 | 55.2 | 296 | 47.1 | ||||
| Gestational weeks on counselling time (Mean, SD) | 8.8 ± 4.6 | 9.0 ± 3.8 | 0.696 | |||||
| Number of co-exposure drugs (Mean, SD) | 9.8 ± 8.5 | 9.7 ± 8.1 | 0.923 | |||||
a
BMI, Body Mass Index. The pre-pregnancy BMI was classified according to Asia-specific standards (WHO Expert Consultation, 2004).