Influence of LAPHs on hematologic parameters in rat liver in a model of paracetamol-induced hepatotoxicitya.
| Groups | RBC (106 μl−1) | Ht (%) | Hb (g dl−1) | CMV (fentolitre) | WBC (103 μl−1) | Plt (103 mm−3) |
|---|---|---|---|---|---|---|
| Control | 8.65 ± 0.37a | 40.7 ± 0.86a | 13.7 ± 0.95a | 55.1 ± 0.85g | 10.32 ± 0.5g | 645 ± 22.3e |
| Paracetamol (P) | 5.23 ± 0.47e | 36.6 ± 0.8d | 9.6 ± 0.9e | 22.1 ± 0.97f | 13.56 ± 0.13a | 1234 ± 31.6a |
| PH-LA/(P) | 6.98 ± 0.44d | 38.6 ± 0.57b | 10.32 ± 0.81d | 38.9 ± 0,67e | 11.62 ± 0.48c | 820 ± 43.6g |
| PH-TR (P−1) | 7.31 ± 0.63c | 40.5 ± 0.35a | 10.97 ± 0.68c | 40.1 ± 0.69c | 11.32 ± 0.72d | 836 ± 63.1f |
| PH-ES (P−1) | 8.07 ± 0.42b | 37.6 ± 0.97c | 12.95 ± 0.67a | 47.32 ± 0,37a | 10.67 ± 0.35f | 969 ± 38.6c |
| PH-A2/(P) | 8.32 ± 0.19a | 39.6 ± 0.81ab | 10.99 ± 0.63c | 39.6 ± 0,77d | 12.36 ± 0.29b | 987 ± 55.32b |
| PH-A26/(P) | 8.04 ± 0.72ab | 38.1 ± 0.44bc | 11.27 ± 0.52b | 45.12 ± 0.15b | 10.93 ± 0.77e | 852 ± 34.33d |
a
RBC, red blood cell; WBC, white blood cell; Ht, hematocrit; Hb, hemoglobin; CMV, mean cell volume; Plt, platelets. Data are expressed as mean ± SD in each group (n = 6). a,b,c,d,e,f,g The means with no common superscripts differ significantly (p < 0.01)