Table 4.

Uni- and multivariate linear regression analysis of the association of comorbidities, echocardiographic parameters and LV reverse remodeling.

	Univariate			Multivariate
	beta	95% CI	p	beta	95% CI	p
Δ LV–GLS
Clinical parameters
Age (years)	0.02	−0.082–0.119	0.712
Female sex	0.63	−0.641–1.894	0.325
BMI (kg/m2)	−0.10	−0.212–0.008	0.069
Hypertension	−1.91	−4.215–0.395	0.102
Atrial fibrillation	−0.53	−1.319–0.256	0.181
Prior AMI	−0.81	−2.344–0.718	0.291
Baseline imaging parameters
Elevated LA stiffness	−0.35	−1.741–1.048	0.620
EF (%)	0.03	−0.041–0.096	0.430
LAVi (mL/m2)	−0.03	−0.062–0.010	0.154
E/e' ratio	0.00	−0.078–0.085	0.933
Severely reduced LASr (<20%)	0.41	−0.907–1.717	0.538
LVMi (g/m2)	−0.01	−0.025–0.001	0.078
LV–GLS (%)	−0.03	−0.217–0.165	0.786
Change in imaging parameters
Δ LVMi (g/m2)	0.01	−0.020–0.038	0.517
Δ LASr (%)	0.13	0.069–0.184	<0.001
Δ LVMi
Clinical parameters
Age (years)	0.17	−0.304–0.646	0.475
Female sex	0.52	−5.677–6.716	0.868
BMI (kg/m2)	0.04	−0.500–0.585	0.876
Hypertension	2.32	−7.022–11.657	0.622
Prior AMI	−5.05	−12.387–2.278	0.174
Baseline imaging parameters
Elevated LA stiffness	−0.03	−7.707–7.639	0.993
EF (%)	0.11	−0.183–0.399	0.461
LAVi (mL/m2)	0.03	−0.118–0.170	0.718
E/e' ratio	0.33	−0.116–0.780	0.144
Severely reduced LASr (<20%)	7.37	1.306–13.432	0.018	5.78	0.397–11.166	0.036
LVMi (g/m2)	0.13	0.077–0.185	<0.001	0.12	0.071–0.177	<0.001
LV–GLS (%)	1.05	−0.007–2.106	0.051
Change in imaging parameters
Δ LV–GLS (%)	−0.35	−2,134–1.435	0.695
Δ LASr (%)	0.04	−0.346–0.421	0.844

Variables with p < 0.05 in univariate analysis were entered into the multivariate model.

AMI, Acute myocardial infarction; BMI, Body mass index; EF, Ejection fraction; LA, Left atrium; LASr, Left atrial peak reservoir strain; LAVi, Left atrial volume index; LV, Left ventricle; LV–GLS, Left ventricular global longitudinal strain; LVMi, Left ventricular mass index. Numbers marked in bold are significant predictors of the outcome.