Fig. 6. H&E staining images and analysis. (A) HE of different organs of mice treated with NaCl, DOX (5 mg kg−1), ITZ (2.5 mg kg−1) and ITZ/DOX-PLip DOX (5 mg kg−1), ITZ (2.5 mg kg−1) (all tissues: ×100). Black circles represent the necrosis zones in tumors and hearts. Black arrows represent metastases in livers. (B) HE whole slide digital analysis of necrosis area of tumors. Each bar represents mean necrosis area ± standard deviation (n = 3). **p < 0.01.
