TABLE 1.
Demographics of patients with organ dysfunction by day 3 of PICU admission.
| All patients (n = 7897) | Survivors (n = 7431) | Non-survivors (n = 466) | p-value** | |
| Age, median [IQR*] (years) | 6.5 (1.6–13.0) | 6.5 (1.6–13.0) | 4.7 (1.0–11.9) | 0.002 |
| Sex, male (n, %) | 4274 (54.1%) | 4014 (54.0%) | 260 (55.8%) | 0.48 |
| Race | ||||
| Black/African American | 2586 (32.7%) | 2440 (32.8%) | 146 (31.3%) | 0.04 |
| White | 2536 (32.1%) | 2392 (32.35) | 144 (30.9%) | |
| Hispanic/Latino | 2021 (25.6%) | 1907 (25.7%) | 114 (24.5%) | |
| Other/Unknown | 754 (9.5%) | 692 (9.3%) | 62 (13.3%) | |
| LOS, median [IQR] (days) | 7.7 (4.1–15.1) | 7.8 (4.3–15.1) | 4.3 (1.5–19.0) | <0.001 |
| Mechanical ventilation days, median [IQR] | 1.0 (0–5.0) | 1.0 (0.0–5.0) | 4.0 (1.0–13.0) | <0.001 |
| PRISM III score, median (IQR) | 6.0 (2.0–11.0) | 6.0 (2.0–10.0) | 19.0 (9.0–28.0) | <0.001 |
| Organ dysfunction incidence by day 3 (n, %) | ||||
| Endocrinologic | 4790 (60.7%) | 4414 (59.4%) | 376 (80.7%) | <0.001 |
| Cardiovascular | 4015 (50.8%) | 3634 (48.9%) | 381 (81.8%) | <0.001 |
| Immunologic | 3878 (49.1%) | 3617 (48.7%) | 261 (56.0%) | 0.002 |
| Neurologic | 3800 (48.1%) | 3440 (46.3%) | 360 (77.3%) | <0.001 |
| Respiratory | 3292 (41.7%) | 2933 (39.5%) | 359 (77.0%) | <0.001 |
| Hematologic | 2799 (35.4%) | 2519 (33.9%) | 280 (60.1%) | <0.001 |
| Renal | 2505 (31.7%) | 2273 (30.6%) | 232 (49.8%) | <0.001 |
| Coagulation | 808 (10.2%) | 689 (9.3%) | 119 (25.5%) | <0.001 |
| Liver | 562 (7.1%) | 403 (5.4%) | 159 (34.1%) | <0.001 |
*IQR, interquartile range.
**Chi-squared performed for categorical variables.
Kruskal–Wallis performed for continuous variables.
p-value > 0.05 considered significant.