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. 2022 Apr 25;13:861435. doi: 10.3389/fneur.2022.861435

Table 1.

Patients' demographics and characteristics.

No infection Non-Cerebral infection VRI
ALL n = 85 n = 97 n = 81
Age [years] 60 ± 14.9 61 ± 12.3 56 ± 12.9
Gender (Male) 39 (45.9) 45 (46.4) 36 (44.4)
Charlson comorbidity index 0 [0, 1.5] 0 [0, 1] 0 [0, 1]
Type of hemorrhage a SAH 52 (61.2) 67 (69.1) 68 (84.0)
ICH 33 (38.8) 30 (30.9) 13 (16.0)
Initial GCS ≤ 8 35 (41.2) 53 (54.6) 37 (45.7)
Ventricular extension 48 (56.5) 60 (61.9) 46 (56.8)
EVD days in situ [d] a, b, c 11 ± 7.4 16 ± 12.4 18 ± 14.7
Antibiotic treatment a, c 49 (57.6) 96 (99.0) 56 (69.1)
NCCU length of stay [d] a, b, c 17 ± 11.3 23 ± 11.5 24 ± 13.0
Hospital length of stay [d] b 25 ± 13.9 30 ± 16.3 33 ± 17.4
SAH n = 52 n = 67 n = 68
Age [years] 60 ± 14.1 61 ± 12.4 57 ± 13.3
Gender (Male) 20 (38.5) 24 (35.8) 27 (39.7)
Charlson comorbidity index 0 [0, 1.75] 0 [0, 1] 0 [0, 1]
Fisher grade 1 1 (1.9) 0 (0.0) 1 (1.5)
2 2 (3.8) 0 (0.0) 3 (4.4)
3 21 (40.4) 27 (40.3) 32 (47.1)
4 28 (53.8) 36 (53.7) 32 (47.1)
WFNS grade 1 4 (7.7) 10 (14.9) 21 (30.9)
2 14 (26.9) 10 (14.9) 10 (14.7)
3 2 (3.8) 4 (6.0) 2 (2.9)
4 17 (32.7) 17 (25.4) 18 (26.5)
5 15 (28.8) 22 (32.8) 17 (25.0)
Ventricular extension 22 (42.3) 35 (52.2) 35 (51.5)
EVD days in situ [d] a 13 ± 7.8 17 ± 7.3 18 ± 15.4
Antibiotic treatment a, c 28 (53.8) 67 (100) 47 (69.1)
NCCU length of stay [d] 20 ± 12.1 24 ± 12.0 24 ± 13.1
Hospital length of stay [d] 27 ± 13.9 32 ± 17.7 32 ± 17.1
ICH n = 33 n = 30 n = 13
Age [years] 61 ± 16.2 58 ± 11.9 53 ± 10.9
Gender (Male) 19 (57.6) 21 (70.0) 9 (69.2)
Charlson comorbidity index 0 [0, 1.5] 0 [0, 1] 0 [0, 1.5]
Initial GCS ≤ 8 15 (45.5) 18 (60.0) 9 (70)
Ventricular extension 26 (78.8) 25 (83.3) 11 (84.6)
EVD days in situ [d] a, b 8 ± 5.7 16 ± 19.7 15 ± 10.1
Antibiotic treatment a, c 21 (63.6) 29 (96.7) 9 (69.2)
NCCU length of stay [d] a 22 ± 13.8 24 ± 10.9 35 ± 19.1
Hospital length of stay [d] 22 ± 13.8 24 ± 10.9 34 ± 19.1
a

p-value is significant for no infection vs. non-cerebral infection,

b

p-value is significant for no infection vs. VRI,

c

p-value is significant for non-cerebral infection vs. VRI, VRI ventriculostomy-related infection; SAH, subarachnoid hemorrhage; ICH, intracerebral hemorrhage; EVD, external ventricular drain; GCS, Glasgow Coma Scale; NCCU, neurocritical care unit.