Table 2.
All patients (SAH and ICH) |
No infection (0) |
Infection, noVRI (1) |
VRI (2) |
p-value | p -value of subgroup-comparison | ||
n = 85 | n = 97 | n = 81 | KW-test | 0 vs. 1 | 0 vs. 2 | 1 vs. 2 | |
Plasma CRP | 116 ± 92.1 | 176 ± 106.1 | 134 ± 96.5 | <0.001 | <0.001 | 0.525 | 0.013 |
Plasma PCT | 1.3 ± 3.32 | 5.7 ± 23.52 | 2.6 ± 12.03 | 0.002 | 0.076 | 0.667 | 0.002 |
Plasma WBC | 15 ± 4.8 | 24 ± 45.8 | 16 ± 5.1 | 0.001 | <0.001 | 0.537 | 0.059 |
CSF WBC | 362 ± 1205.4 | 514 ± 1562.3 | 2041 ± 10250.8 | <0.001 | 0.418 | <0.001 | <0.001 |
SAH | No infection (0) |
Infection, noVRI (1) |
VRI (2) | p-value | p -value of subgroup-comparison | ||
n = 52 | n = 67 | n = 68 | KW-test | 0 vs. 1 | 0 vs. 2 | 1 vs. 2 | |
Plasma CRP | 116 ± 90.1 | 171 ± 104.2 | 140 ± 99.9 | 0.005 | 0.004 | 0.524 | 0.137 |
Plasma PCT | 1.1 ± 2.23 | 2.0 ± 4.63 | 3.0 ± 13.09 | 0.035 | 0.600 | 0.770 | 0.029 |
Plasma WBC | 16 ± 5.2 | 20.9 ± 34.7 | 16 ± 5.4 | 0.180 | |||
CSF WBC | 336 ± 700.8 | 685 ± 1855.9 | 2174 ± 11096.5 | <0.001 | 1.000 | <0.001 | <0.001 |
ICH | No infection (0) |
Infection, noVRI (1) |
VRI (2) | p-value | p -value of subgroup-comparison | ||
n = 33 | n = 30 | n = 13 | KW-test | 0 vs. 1 | 0 vs. 2 | 1 vs. 2 | |
Plasma CRP | 115 ± 96.7 | 189 ± 111.0 | 107 ± 73.6 | 0.008 | 0.013 | 1.000 | 0.077 |
Plasma PCT | 1.7 ± 4.57 | 13.9 ± 41.01 | 1.0 ± 2.07 | 0.037 | 0.107 | 1.000 | 0.084 |
Plasma WBC | 13 ± 3.7 | 30 ± 63.8 | 13 ± 2.2 | 0.001 | 0.001 | 1.000 | 0.012 |
CSF WBC | 403 ± 1740.3 | 134 ± 155.8 | 1348 ± 3522.6 | 0.006 | 0.416 | 0.004 | 0.135 |
SAH vs. ICH | No infection | Infection, no VRI | VRI | ||||
MWU-test | p-value | p-value | p-value | ||||
Plasma CRP | 0.735 | 0.492 | 0.368 | ||||
Plasma PCT | 0.749 | 0.200 | 0.657 | ||||
Plasma WBC | 0.031 | 0.410 | 0.016 | ||||
CSF WBC | 0.001 | 0.010 | 0.052 |
Statistics are performed using either a Kruskall Wallis test or a Mann-Whitney- U test, subgroup p-values are shown adjusted for multiple comparison using Bonferroni correction. CRP is described in mg/l, PCT in μg/l, WBC in G/l, and CSF WBC in n/μl. VRI, ventriculostomy related infection; SAH, subarachnoid hemorrhage; ICH, intracerebral hemorrhage; CRP, C-reactive protein; PCT, procalcitonin; WBC, white blood cell count; CSF, cerebrospinal fluid; KW-test, Kruskal Wallis test; MWU-test, Mann-Whitney-U test.