Table 3.
Subgroup analysis of patients with ventriculostomy-related infection (VRI).
| VRI CSF parameters and characteristics |
All n = 81 |
SAH n = 68 |
ICH n = 13 |
p-value | ||
|---|---|---|---|---|---|---|
| Day VRI diagnosis | 9 ± 6.2 | 8 ± 5.5 | 11 ± 8.9 | 0.114 | ||
| Peak CSF WBC day | 8 ± 6.3 | 8 ± 6.3 | 7 ± 6.3 | 0.874 | ||
| Peak CSF WBC | 2063 ± 10313.4 | 2174 ± 11096.5 | 1348 ± 3522.6 | 0.792 | ||
| Neutrophils | 55 ± 26.3 | 55 ± 25.5 | 59 ± 32.1 | 0.656 | ||
| Lymphocites | 27 ± 20.8 | 27 ± 19.6 | 28 ± 28.2 | 0.850 | ||
| Macrophages/Monocytes | 15 ± 8.7 | 16 ± 7.9 | 12 ± 12.5 | 0.270 | ||
| Eosinphiles | 2 ± 7.7 | 2 ± 8.4 | 0 ± 0.3 | 0.638 | ||
| Basophiles | 0 ± 0.5 | 0 ± 0.4 | 0 ± 0.8 | 0.789 | ||
| Plasmaells | 0 ± 0.2 | 0 ± 0.2 | 0 ± 0.0 | 0.355 | ||
| VRI with and without positive CSF culture | VRI without positive culture | VRI with positive culture | p -value | |||
| n = 67 | n = 14 | |||||
| Plasma CRP | 127 ± 89.4 | 174 ± 121.7 | 0.110 | |||
| Plasma PCT | 3.1 ± 13.19 | 0.5 ± 0.66 | 0.499 | |||
| Plasma WBC | 15 ± 4.5 | 19 ± 7.0 | 0.078 | |||
| CSF WBC | 742 ± 652.3 | 8263 ± 24373.8 | 0.181 | |||
| Day of VRI Dig | 8 ± 5.8 | 12 ± 7.5 | 0.137 | |||
| Peak WBC day | 7 ± 5.4 | 11 ± 8.8 | 0.232 | |||
| Peak WBC | 748 ± 652.2 | 8263 ± 24373.8 | 0.314 | |||
| Neutrophils | 54 ± 24.4 | 60 ± 32.4 | 0.476 | |||
| Lymphocites | 27 ± 18.2 | 28 ± 28.4 | 0.576 | |||
| Macrophages/Monocytes | 16 ± 7.5 | 12 ± 11.8 | 0.094 | |||
| Eosinphiles | 2 ± 8.9 | 0 ± 0.6 | 0.919 | |||
| Basophiles | 0 ± 0.5 | 0 ± 0.2 | 0.416 | |||
| Plasmaells | 0 ± 0.2 | 0 ± 0.0 | 0.492 |
Statistics are performed using a t-test or a Mann-Whitney- U test. CRP is described in mg/l, PCT in μg/l, WBC in G/l, and CSF WBC in n/μl. VRI, ventriculostomy related infection; SAH, subarachnoid hemorrhage; ICH, intracerebral hemorrhage; CRP, C-reactive protein; PCT, procalcitonin; WBC, white blood cell count; CSF, cerebrospinal fluid.