Echocardiographic characteristics of three group rats with 8 weeks treatmenta.
| Control group (n = 13) | DOX group (n = 9) | DOX + TQ group (n = 12) | |
|---|---|---|---|
| LVEF (%) | 95.63 ± 3.89 | 63.67 ± 3.09* | 87.13 ± 2.09** |
| LVFS (%) | 66.5 ± 2.35 | 30.63 ± 4.16* | 54.5 ± 2.62** |
| LVESD (mm) | 1.5 ± 0.13 | 2.68 ± 0.17* | 2.44 ± 0.2* |
| LVEDD (mm) | 3.82 ± 0.22 | 4.67 ± 0.12* | 4.24 ± 0.22* |
a
LVEF = left ventricular ejection fraction; LVFS = left ventricular fractional shortening; LVEDD = left ventricular end-diastolic dimension; LVESD = left ventricular end-systolic dimension. Data are given as the means ± SEM; n = 9–13 in each group. *P < 0.05 vs. Control group; **P < 0.05 vs. DOX group.