Table 3.
Secondary outcomes.
| Variables | Non-adjusted | Model 1 | Model 2 | |||
|---|---|---|---|---|---|---|
| OR | P -Value | OR | P -Value | OR | P -Value | |
| 90-day mortality | ||||||
| 0.5–1.0 | Ref. | Ref. | Ref. | |||
| <0.5 | 3.558 (3.116–4.064) | <0.001 | 3.485 (3.044–3.989) | <0.001 | 1.893 (1.613–2.222) | <0.001 |
| 1.0–1.5 | 0.718 (0.604–0.853) | <0.001 | 0.738 (0.620–0.878) | 0.001 | 0.833 (0.690–1.005) | 0.057 |
| 1.5–2.0 | 0.724 (0.577–0.908) | 0.005 | 0.763 (0.607–0.960) | 0.021 | 0.828 (0.647–1.060) | 0.133 |
| ≥2.0 | 1.814 (1.517–2.169) | <0.001 | 2.052 (1.709–2.465) | <0.001 | 1.619 (1.301–2.015) | <0.001 |
| ICU mortality | ||||||
| 0.5–1.0 | Ref. | Ref. | Ref. | |||
| <0.5 | 4.072 (3.396–4.884) | <0.001 | 3.914 (3.260–4.700) | <0.001 | 1.545 (1.231–1.939) | <0.001 |
| 1.0–1.5 | 0.656 (0.505–0.852) | 0.002 | 0.670 (0.515–0.871) | 0.003 | 0.751 (0.563–1.002) | 0.052 |
| 1.5–2.0 | 0.561 (0.388–0.812) | 0.002 | 0.582 (0.401–0.843) | 0.004 | 0.622 (0.417–0.926) | 0.019 |
| ≥2.0 | 1.998 (1.561–2.558) | <0.001 | 2.150 (1.675–2.761) | <0.001 | 1.109 (0.790–1.557) | 0.551 |
| Hospital mortality | ||||||
| 0.5–1.0 | Ref. | Ref. | Ref. | |||
| <0.5 | 3.950 (3.357–4.648) | <0.001 | 3.812 (3.234–4.494) | <0.001 | 1.698 (1.386–2.080) | <0.001 |
| 1.0–1.5 | 0.633 (0.501–0.799) | <0.001 | 0.648 (0.513–0.819) | <0.001 | 0.737 (0.570–0.953) | 0.020 |
| 1.5–2.0 | 0.632 (0.464–0.861) | 0.004 | 0.660 (0.484–0.901) | 0.009 | 0.716 (0.510–1.004) | 0.053 |
| ≥2.0 | 1.561 (1.234–1.975) | <0.001 | 1.707 (1.345–2.167) | <0.001 | 0.899 (0.650–1.244) | 0.522 |
| Ventilation | ||||||
| 0.5–1.0 | Ref. | Ref. | Ref. | |||
| <0.5 | 1.258 (1.141–1.386) | <0.001 | 1.230 (1.116–1.357) | <0.001 | 1.720 (1.458–2.029) | <0.001 |
| 1.0–1.5 | 0.943 (0.859–1.034) | 0.212 | 0.940 (0.856–1.032) | 0.191 | 0.903 (0.775–1.052) | 0.192 |
| 1.5–2.0 | 0.982 (0.872–1.107) | 0.772 | 0.974 (0.863–1.098) | 0.665 | 1.092 (0.894–1.333) | 0.388 |
| ≥2.0 | 1.360 (1.204–1.536) | <0.001 | 1.331 (1.177–1.505) | <0.001 | 1.647 (1.333–2.035) | <0.001 |
| Vasopressor | ||||||
| 0.5–1.0 | Ref. | Ref. | Ref. | |||
| <0.5 | 1.096 (0.995–1.207) | 0.063 | 1.087 (0.986–1.198) | 0.093 | 1.358 (1.194–1.545) | <0.001 |
| 1.0–1.5 | 0.995 (0.908–1.090) | 0.917 | 0.979 (0.893–1.073) | 0.649 | 0.943 (0.842–1.056) | 0.331 |
| 1.5–2.0 | 0.925 (0.821–1.041) | 0.193 | 0.889 (0.790–1.002) | 0.054 | 0.825 (0.712–0.956) | 0.011 |
| ≥2.0 | 1.178 (1.043–1.330) | 0.008 | 1.093 (0.967–1.236) | 0.156 | 0.971 (0.829–1.138) | 0.719 |
Model 1: age, gender. Model 2: age, male, Simplified Acute Physiology Score, Sequential Organ Failure Assessment score, temperature, respiratory rate, mean aortic pressure, heart rate, oxyhemoglobin saturation, congestive heart failure, ventricular arrhythmia, acute myocardial infarction, chronic obstructive pulmonary disease, sepsis, acute kidney injury, chronic kidney disease, liver diseases, stroke, malignancy, white blood cell, sodium, potassium, creatinine, diuretic.