Effect of hesperetin and 5-FU individually or combined on liver and kidney functiona.
| Group | ALT (U l−1) | AST (U l−1) | Urea (μmol l−1) | Cr (μmol l−1) |
|---|---|---|---|---|
| Control | 41.33(11.93) | 142.67(9.87) | 9.21(0.74) | 10.67(0.58) |
| 5-FU | 42.01(4.12) | 142.47(10.34) | 9.64(0.67) | 10.25(0.83) |
| Hesperetin | 40.53(2.57) | 143.35(7.79) | 8.33(1.18) | 11.5(0.5) |
| Combined | 40.78(2.83) | 142.98(2.83) | 9.36(0.38) | 10.83(1.04) |
a
Data are presented as mean (standard deviation). ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; Cr, serum creatinine. No differences were observed in any laboratory value between the groups (p > 0.05).