Figure 3.

CGRP injection into the MN did not induce gait alterations. Stride length (A) and frequency (B) for all mice following injection of PBS (n = 10) or CGRP (1 μg/200 nl; n = 16) into the right MN of C57BL/6J mice via cannulas. Stride length (C) and frequency (D) for female mice (PBS: n = 6; CGRP: n = 9). Stride length (E) and frequency (F) for male mice (PBS: n = 4; CGRP: n = 7). Injection of CGRP into the MN did not change the stride length and frequency comparing before and after CGRP or PBS treatments across and within sexes. It suggests that CGRP in the MN did not change the gait. LF, left front paw; RF, right front paw; LH, left hind paw; RH, right hind paw. Data are the mean ± SEM. Statistics are described in Supplementary Table 1. Data are from one experiment.