TABLE 3.

Predicted Kyoto Encyclopedia of Genes and Genome (KEGG) Pathways differentially abundant between H. pylori positive group and H. pylori negative group.

KEGG_Pathways	H. pylori positive group	H. pylori negative group	P-values
meanrel.freq (%)	mean rel.freq (%)	(corrected)
Membrane transport	12.81020	14.31537	0.00111
Carbohydrate metabolism	8.83796	9.43903	0.00002
Transcription	2.13442	2.49131	0.00112
Xenobiotics biodegradation and metabolism
	3.15179	3.83444	0.00173
Poorly characterized	4.98596	5.36991	0.00265
Metabolism	2.39862	2.64914	0.00049
Amino acid metabolism	9.80064	10.23009	0.00049
Lipid metabolism	3.36831	3.68045	0.00180
Biosynthesis of other secondary metabolites
	0.65649	0.82317	0.00012
Enzyme families	1.77929	1.88921	0.00381
Metabolism of other amino acids	1.87500	1.96659	0.00200
Excretory system	0.01603	0.02382	0.00061
Replication and repair	7.29078	6.24300	0.00062
Translation	4.56422	3.68849	0.00064
Genetic information processing	2.82985	2.29201	0.00037
Cell Motility	4.13253	3.25663	0.00040
Glycan biosynthesis and metabolism
	2.48850	1.95081	0.00013
Nucleotide metabolism	3.26567	2.89224	0.00158
Folding, sorting, and degradation	2.52035	2.17161	0.00064
Neurodegenerative diseases	0.48127	0.33344	0.00006
Circulatory system	0.08617	0.04169	0.00009
Cell growth and death	0.51918	0.47573	0.00667
Cancers	0.18649	0.16378	0.00029
Signaling molecules and interaction
	0.22618	0.14939	0.00031
Environmental adaptation	0.15010	0.11174	0.00029
Immune system diseases	0.04799	0.04354	0.00136
Immune system	0.07013	0.04844	0.00020
Endocrine system	0.24280	0.31562	0.00062
Metabolism of terpenoids and polyketides
	1.83871	2.01114	0.00085
Cardiovascular diseases	0.01576	0.02158	0.00805
Infectious diseases	0.55379	0.52832	0.00653
Transport and catabolism	0.22724	0.25596	0.0001
Nervous system	0.08059	0.09231	0.00019
Digestive system	0.02069	0.03328	0.00594