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. 2022 Apr 25;13:853184. doi: 10.3389/fmicb.2022.853184

TABLE 4.

The selected clusters of orthologous groups (COG) and Kyoto Encyclopedia of Genes and Genome orthology (KO) functions predicted with the whole bacterial community.

Selected COG functions predicted with the whole bacterial community
#COG Z-Value P-value Enriched category
COG0600 −3.744 0.0001 H. pylori negative group
COG0715 −3.679 0.0001 H. pylori negative group
COG1116 −3.744 0.0001 H. pylori negative group
COG1140 −3.550 0.0001 H. pylori negative group
COG1251 −3.486 0.0001 H. pylori negative group
COG2116 −3.422 0.0001 H. pylori negative group
COG2146 −3.679 0.0001 H. pylori negative group
COG2180 −3.550 0.0001 H. pylori negative group
COG2181 −3.551 0.0001 H. pylori negative group
COG2223 −3.550 0.0001 H. pylori negative group
COG3005 −3.034 0.0001 H. pylori negative group
COG3043 −2.776 0.004 H. pylori negative group
COG3062 −2.711 0.005 H. pylori negative group
COG3301 −2.711 0.005 H. pylori negative group
COG3303 −0.291 0.776
COG4459 −2.969 0.002 H. pylori negative group
COG5013 −3.550 0.0001 H. pylori negative group

Selected KO functions predicted with the whole bacterial community

#KO Z-Value P-value Enriched category

K00362 −3.357 0.0001 H. pylori negative group
K00363 −3.098 0.0001 H. pylori negative group
K00368 −3.679 0.0001 H. pylori negative group
K00370 −3.228 0.001 H. pylori negative group
K00371 −3.228 0.001 H. pylori negative group
K00374 −3.227 0.001 H. pylori negative group
K02575 −3.648 0.0001 H. pylori negative group
K03385 −0.581 0.591

Predicted metagenome of the gastric microbiota using COG in Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt). Predicted COG and KO functions were analysed in STAMP using the two-group comparison with Kruskal-Wallis Test.