Fig. 6. Pathway analysis of metabolic variations in ovariectomy-induced osteoporosis in female Wistar rats. Note: (1) valine, leucine and isoleucine biosynthesis; (2) arachidonic acid metabolism; (3) primary bile acid biosynthesis; (4) glycerophospholipid metabolism; (5) steroid hormone biosynthesis; (6) biosynthesis of unsaturated fatty acids; (7) biotin metabolism; (8) taurine and hypotaurine metabolism; (9) aminoacyl-tRNA biosynthesis; (10) fatty acid elongation in mitochondria; (11) valine, leucine and isoleucine degradation; (12) fatty acid metabolism; (13) fatty acid biosynthesis.