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. 2022 Apr 25;12:861601. doi: 10.3389/fonc.2022.861601

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Copyright © 2022 Jin, Zhang, Wang, Guan, Shao, Lin, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High TGF-β1 expression is positively correlated with active immunity in HCC patients. (A) GO (Gene Ontology) analyses using e1071, Parallel, and Preprocesscore packages revealed the involvement of TGF-β1 in activation of various immune-related signal pathways. BP, biological process; CC, cellular component; MF, molecular function. (B) Top ten activated and top ten suppressed signal pathways by high TGF-β1 level were presented, respectively, using Gene Set Enrichment Analysis (GSEA) software and KEGG database.