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. 2022 Mar 30;91(6):772–781. doi: 10.1002/ana.26350

FIGURE 1.

FIGURE 1

COVID‐19‐associated alterations in NDEV levels of proteins involved in mitochondrial dynamics, energy generation, metabolism, and maintenance of neuronal survival. Each point represents the value for one study participant after CD81 (A) normalization (B‐G). The horizontal line in each column of points depicts mean value. Statistical significance of the difference in level for each group was calculated relative to Ctl values by an unpaired t test; NS, not significant; +p <0.05; *p <0.01; **p <0.001. The significance (p values) of differences between participants who had PASC w/ neuropsychiatric (NP) findings and those who had PASC w/o NP and between participants who had PASC w/ NP and those who had PASC w/ severe NP, respectively, were: <0.01 and <0.01 for CD81 (A); <0.0001 and NS for syntaphilin (SNPH) (B); NS and <0.05 for myosin 6 (Myo 6) (C); <0.05 and NS for subunit 6 of NADH–ubiquinone oxidoreductase (respiratory chain complex I) (CI‐6) (D); <0.05 and <0.05 for subunit 10 of cytochrome b‐c1 oxidase (respiratory chain complex III) (CIII‐10) (E); <0.01 and <0.001 for mitochondrial open‐reading frame of the 12S rRNA‐c (MOTS‐c) (F); and <0.01 and <0.001 for 16S rRNA‐encoded Humanin (G). NP = neuropsychiatric abnormalities.