TABLE 2.

Summary of antibiotic MICs for S. aureus mutants selected by BMS-284756

Strain	MIC (μg/ml) of:
	BMS-284756	Ciprofloxacin	Levofloxacin	Moxifloxacin
Parental strain
ISP794	0.007	0.125	0.125	0.06
First-step strain
1(756)1	0.015	0.06	0.125	0.03
Second-step strains
2(756)1-6	0.015	0.125	0.125	0.03
2(756)1-10	0.015	0.125	0.125	0.03
Third-step strains
3(756)6-1	0.06	0.125	0.125	0.03
3(756)6-2	0.06	0.25	0.125	0.03
3(756)6-3	0.03	0.5	0.5	0.06
3(756)10-1	0.06	0.25	0.125	0.03
3(756)10-2	0.06	0.25	0.125	0.03
3(756)10-3	0.06	0.25	0.125	0.03
3(756)10-4	0.06	0.25	0.125	0.03
Fourth-step strains
4(756)6-1	1.0	1.0	1.0	1.0
4(756)6-2	1.0	8.0	4.0	2.0
4(756)6-3	1.0	1.0	1.0	1.0
4(756)10-1	1.0	2.0	2.0	1.0
4(756)10-2	1.0	1.0	1.0	1.0
4(756)10-3	1.0	8.0	4.0	2.0
Fifth-step strains
5(756)6-1	2.0	2.0	1.0	2.0
5(756)6-2	2.0	2.0	1.0	2.0
5(756)6-3	2.0	2.0	1.0	2.0
5(756)10-1	2.0	2.0	2.0	2.0
5(756)10-2	2.0	2.0	2.0	1.0
5(756)10-3	2.0	2.0	2.0	2.0