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. 2018 Jul 11;8(44):24913–24922. doi: 10.1039/c8ra04389b

K d (nM) values for thiodigalactosides 1, 19–20, and 22–23 determined by competitive fluorescence polarization.

Galectin-1 Galectin-3 Galectin-3/galectin-1
1 6.1 ± 1 59 ± 4 9.7
19 8.4 ± 1 74 ± 4 8.8
20 25 ± 2 180 ± 10 7.2
22 12 ± 1 61 ± 3 5.1
23 13 ± 1 1.8 ± 0.2 0.14
TDG 24 000 13 49 000 13 2