Fig. 4.
Distribution of use-categories for ToxCast Phase II (ph1v2, ph 2) chemicals. Only the top 10 use-categories (by chemical representation) are shown, with the remaining listed as “Other”; the numbers of chemicals in each use-category is labeled. (A) ToxCast ph1v2 and ph 2 full test set. (B) RAIU inhibition (RAIUi) active compounds in multi-concentration screening (Hit1 actives). (C) Non-cytotoxic RAIU inhibition active compounds in multi-concentration screening (Hit2 actives).