Table 2 ∣.

Clinical presentation and genotype of GNA11/GNAQ/GNAS in the APA of 17 patients with PA who had CTNNB1-mutant APAs from the replication cohorts

Replication cohort	Patient no.	Sex	Age (years)	Hypertensive at pregnancy (number of pregnancies)	Tumor genotype
					CTNNB1	GNA11 Q209	GNA11 R183	GNAQ Q209	GNAQ R183	GNAS Q227	GNAS R201
French cohort	F1	Female	29	Yes (1)	S45F	WT	WT	WT	WT	WT	WT
	F2	Male	40	–	S45P	WT	WT	WT	WT	WT	WT
	F3	Female	35	No (2)	S37C	WT	WT	WT	WT	WT	WT
	F4	Male	33	–	S45A	WT	WT	WT	WT	WT	WT
	F5	Female	43	No (1)	S45F	Q209P	WT	WT	WT	WT	WT
	F6	Female	45	Yes (2)	S45P	WT	WT	WT	WT	WT	WT
	F7	Female	55	NA	S45P	WT	WT	WT	WT	WT	WT
	F8	Female	55	NA	S45P	WT	WT	WT	WT	WT	WT
	F9	Female	26	Yesa (1)	S37P	WT	WT	Q209H	WT	WT	WT
	F10	Female	51	Yes (1)	S45P	Q209H	WT	WT	WT	WT	WT
	F11	Male	36	–	S45P	WT	WT	WT	WT	WT	WT
	F12	Female	56	No (10)	D32Y	Q209H	WT	WT	WT	WT	WT
	F13	Female	56	No (0)	S45Y	WT	WT	WT	WT	WT	WT
	F14	Female	17	Nob (0)	G34V	WT	WT	Q209H	WT	WT	WT
Swedish cohort	S1	Female	55	Yesc (2)	S45P	WT	WT	Q209H	WT	WT	WT
	S2	Female	59	NA	S45P	WT	WT	WT	WT	WT	WT
	S3	Female	26	NA	S37F	WT	WT	WT	WT	WT	WT

WT, wild type.

^aPre-eclampsia.

^bHypertensive at puberty.

^cOnset at age 24 years preceding first pregnancy.