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Calculated parameters of in vitro HTLV-1 IN strand-transfer and HTLV-1 infection inhibition by INSTIs and one NRTI.
| Antiretroviral | IC50 ± SDa (nM) | EC50 ± SDb (nM) |
| Raltegravir | 530 ± 102c | 6.42 ± 4.24c |
| Elvitegravir | 100 ± 16c | 9.57 ± 5.54c |
| Bictegravir | 180 ± 29c | 0.302 ± 0.173c |
| Cabotegravir | 78 ± 24 | 0.557 ± 0.255 |
| Tenofovir disoproxil fumarate | NR | 17.78 ± 7.16c |
aIC50 = half maximal inhibitory concentration. bEC50 = half maximal effective concentration. cBarski et al. (16).
