TABLE 1.
Descriptive statistics by pathologic stage for resected PACC
| Covariate | Level | Stage I |
p value | Stage IIA |
p value | Stage IIB |
p value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| S + T N = 48 | SA N = 53 | S + T N = 52 | SA N = 29 | S + T N = 59 | SA N = 30 | |||||
|
| ||||||||||
| Age | <65 | 26 (54.17) | 24 (45.28) | 0.373 | 25 (48.08) | 12 (41.38) | 0.562 | 33 (55.93) | 10 (33.33) | 0.044 |
| ≥65 | 22 (45.83) | 29 (54.72) | 27 (51.92) | 17 (58.62) | 26 (44.07) | 20 (66.67) | ||||
|
| ||||||||||
| Sex | Male | 29 (60.42) | 29 (54.72) | 0.563 | 37 (71.15) | 26 (89.66) | 0.092 | 46 (77.97) | 21 (70) | 0.41 |
| Female | 19 (39.58) | 24 (45.28) | 15 (28.85) | 3 (10.34) | 13 (22.03) | 9 (30) | ||||
|
| ||||||||||
| Race | White | 40 (83.33) | 40 (75.47) | 0.331 | 45 (86.54) | 26 (89.66) | 1 | 53 (89.83) | 27 (90) | 1 |
| Others | 8 (16.67) | 13 (24.53) | 7 (13.46) | 3 (10.34) | 6 (10.17) | 3 (10) | ||||
|
| ||||||||||
| Facility type | Others | 17 (37.78) | 25 (49.02) | 0.268 | 27 (55.1) | 10 (35.71) | 0.101 | 20 (35.09) | 11 (36.67) | 0.884 |
| Academics | 28 (62.22) | 26 (50.98) | 22 (44.9) | 18 (64.29) | 37 (64.91) | 19 (63.33) | ||||
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| ||||||||||
| Charlson-Deyo Score |
0 | 32 (66.67) | 37 (69.81) | 0.896 | 42 (80.77) | 15 (51.72) | 0.016 | 42 (71.19) | 20 (66.67) | 0.677 |
| 1 | 12 (25) | 13 (24.53) | 7 (13.46) | 11 (37.93) | 13 (22.03) | 9 (30) | ||||
| 2+ | 4 (8.33) | 3 (5.66) | 3 (5.77) | 3 (10.34) | 4 (6.78) | 1 (3.33) | ||||
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| Primary payor | Others | 27 (56.25) | 31 (58.49) | 0.82 | 31 (59.62) | 8 (27.59) | 0.006 | 34 (57.63) | 24 (80) | 0.036 |
| Private | 21 (43.75) | 22 (41.51) | 21 (40.38) | 21 (72.41) | 25 (42.37) | 6 (20) | ||||
|
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| Grade | Well differentiated | 7 (30.43) | 9 (36) | 0.92 | 1 (4.55) | 4 (26.67) | 0.212 | 2 (4.88) | 2 (9.52) | 0.334 |
| Moderately differentiated | 11 (47.83) | 11 (44) | 14 (63.64) | 7 (46.67) | 19 (46.34) | 6 (28.57) | ||||
| Poorly differentiated/ undifferentiated | 5 (21.74) | 5 (20) | 7 (31.82) | 4 (26.67) | 20 (48.78) | 13 (61.9) | ||||
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| AJCC clinical T | c0 | 1 (2.13) | 0 (0) | 0.392 | 1 (1.92) | 3 (10.34) | 0.498 | 2 (3.45) | 1 (3.45) | 0.271 |
| c1 | 9 (19.15) | 6 (11.76) | 15 (28.85) | 8 (27.59) | 27 (46.55) | 7 (24.14) | ||||
| c2 | 19 (40.43) | 26 (50.98) | 21 (40.38) | 10 (34.48) | 17 (29.31) | 12 (41.38) | ||||
| c3 | 6 (12.77) | 3 (5.88) | 2 (3.85) | 0 (0) | 2 (3.45) | 1 (3.45) | ||||
| cX | 12 (25.53) | 16 (31.37) | 13 (25) | 8 (27.59) | 10 (17.24) | 8 (27.59) | ||||
|
| ||||||||||
| AJCC clinical N | c0 | 33 (70.21) | 38 (73.08) | 0.651 | 34 (65.38) | 23 (79.31) | 0.484 | 25 (43.1) | 14 (50) | 0.783 |
| c1 | 3 (6.38) | 1 (1.92) | 4 (7.69) | 1 (3.45) | 23 (39.66) | 9 (32.14) | ||||
| cX | 11 (23.4) | 13 (25) | 14 (26.92) | 5 (17.24) | 10 (17.24) | 5 (17.86) | ||||
|
| ||||||||||
| Lymph vascular invasion, 2010 | Not present | 14 (53.85) | 24 (85.71) | 0.03 | 18 (51.43) | 8 (42.11) | 0.584 | 9 (20.93) | 3 (17.65) | 1 |
| Present | 6 (23.08) | 3 (10.71) | 13 (37.14) | 10 (52.63) | 29 (67.44) | 12 (70.59) | ||||
| Unknown | 6 (23.08) | 1 (3.57) | 4 (11.43) | 1 (5.26) | 5 (11.63) | 2 (11.76) | ||||
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| Primary site | Others | 31 (64.58) | 36 (67.92) | 0.723 | 33 (63.46) | 19 (65.52) | 0.853 | 27 (45.76) | 12 (40) | 0.604 |
| Head | 17 (35.42) | 17 (32.08) | 19 (36.54) | 10 (34.48) | 32 (54.24) | 18 (60) | ||||
|
| ||||||||||
| Surgical margin | Negative | 44 (93.62) | 53 (100) | 0.062 | 38 (76) | 23 (92) | 0.122 | 44 (74.58) | 23 (79.31) | 0.624 |
| Positive | 3 (6.38) | 0 (0) | 12 (24) | 2 (8) | 15 (25.42) | 6 (20.69) | ||||
|
| ||||||||||
| Tumor size | >4 | 18 (37.5) | 23 (43.4) | 0.547 | 36 (69.23 | 18 (62.07) | 0.512 | 32 (54.24) | 19 (63.33) | 0.412 |
| ≤4 | 30 (62.5) | 30 (56.6) | 16 (30.77) | 11 (37.93) | 27 (45.76) | 11 (36.67) | ||||
Abbreviations: PACC, pancreatic acinar cell carcinoma; SA, surgery alone; S + T, surgery + therapy.