TABLE 4.
Univariate analysis of additional therapy for resected pIIB PACC
| Cohort | Treatment | N | OS |
||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | HR p value | Log-rank p value | |||
|
| |||||
| Grouped | Chemotherapy | 22 | 0.39 (0.19–0.75) | 0.007 | 0.010 |
| Radiation +che- motherapy | 33 | 0.54 (0.30–0.96) | 0.038 | ||
| Surgery alone | 30 | − | − | ||
|
| |||||
| Subset | Single-agent chemotherapy | 13 | 0.38 (0.16–0.83) | 0.025 | 0.099 |
| Multiagent chemotherapy | 9 | 0.47 (0.17–1.09) | 0.114 | ||
| Radiation + single-agent chemotherapy | 19 | 0.64 (0.32–1.22) | 0.193 | ||
| Radiation + multiagent chemotherapy | 14 | 0.50 (0.22–1.02) | 0.075 | ||
| Radiation only | 2 | 0.54 (0.11–1.70) | 0.372 | ||
| Surgery alone | 30 | − | − | ||
Note: Firth’s penalized maximum likelihood estimation was used.
Abbreviations: CI, confidence interval; HR, hazard ratio; OS, overall survival.