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. 2022 May 5;50(5):03000605221097490. doi: 10.1177/03000605221097490

Table 1.

Anthropometric and biochemical parameters of diabetic mice treated with vehicle or luseogliflozin.

Vehicle Luseogliflozin
Number 9 10
Food intake (g/day) 5.0 5.0
Heart weight index 8.9 ± 0.5 8.6 ± 0.6
Kidney weight index 18.7 ± 1.4 14.7 ± 1.6**
Liver weight index 142.6 ± 11.4 108.3 ± 15.9**
Visceral fat weight index 85.7 ± 5.1 88.7 ± 5.5
Pulse rate (/minute) 597 ± 63 638 ± 38
Systolic blood pressure (mmHg) 127 ± 23 127 ± 23
HbA1c (%) 12.4 ± 0.3 7.8 ± 0.6**
Plasma glucose (mg/dL) 564 ± 49 255 ± 46**
Plasma insulin (ng/mL) 0.3 ± 0.2 0.7 ± 0.6
Plasma total cholesterol (mg/dL) 234 ± 32 230 ± 42
Plasma HDL cholesterol (mg/dL) 139 ± 27 140 ± 29
Plasma triglycerides (mg/dL) 108 ± 38 108 ± 58

Mean ± standard deviation. HDL, high-density lipoprotein; HbA1c, glycated hemoglobin. *p < 0.05, **p < 0.01 vs. Vehicle.