Table 2.
Associations between shift work and cardiovascular disease (CVD) by adjustment models
| Incident CVD |
Fatal CVD |
|||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Model 0 | 1.25 (1.20, 1.30) | <0.0001 | 1.43 (1.25, 1.63) | <0.0001 |
| Model 1 | 1.14 (1.09, 1.19) | <0.0001 | 1.27 (1.11, 1.46) | 0.0005 |
| Model 2 | 1.11 (1.06, 1.16) | <0.0001 | 1.25 (1.08, 1.44) | 0.002 |
| + PA factors | 1.09 (1.04, 1.15) | 0.0006 | 1.24 (1.04, 1.47) | 0.02 |
| + Dietary factors | 1.10 (1.05, 1.15) | <0.0001 | 1.24 (1.07, 1.43) | 0.004 |
| + Smoking/drinking | 1.10 (1.05, 1.15) | <0.0001 | 1.23 (1.06, 1.44) | 0.007 |
| + Sleep factors | 1.09 (1.05, 1.14) | <0.0001 | 1.26 (1.09, 1.46) | 0.002 |
| + Social factors | 1.10 (1.06, 1.15) | <0.0001 | 1.26 (1.09, 1.46) | 0.002 |
| + Adiposity | 1.08 (1.03, 1.13) | 0.0007 | 1.22 (1.05, 1.41) | 0.008 |
| + Physical markers | 1.10 (1.05, 1.16) | <0.0001 | 1.21 (1.04, 1.41) | 0.01 |
| + Serum markers | 1.08 (1.04, 1.14) | 0.0006 | 1.20 (1.03, 1.40) | 0.02 |
Model 0: age and sex only; Model 1: education and deprivation additionally; Model 2: hours of work per week, duration of current job, walking/standing at work, heavy manual/physical work additionally.