Fig. 8. Comparison of the impact of differences between the gut microbiota of the silkworms that were reared fresh mulberry leaves or the artificial diet. (a and b) Phylum-classified and (c and d) family-classified gut microbiota whose relative abundance differed between the silkworms that were reared on fresh mulberry leaves or the artificial diet (the relative abundance of the HiM vs. HiA strains and the GsM vs. GsA are shown, P < 0.05, n = 5). (e) Predicted functional analysis of the silkworm gut microbiomes using the PICRUSt software tool. The bar plot shows the pathways that were enriched significantly by the artificial diet (P < 0.05), as determined by a one-way analysis of variance. The fold-change represents the values of the HiM strain divided by those of the HiA strain, or the values of the GsM strain divided by those of the GsA strain.